Business-to-business (B2B) Software-as-a-Service (SaaS) startups continue to reshape how companies operate, collaborate, and grow. From revolutionizing employee management and sales enablement to pioneering new frontiers in artificial intelligence (AI) infrastructure and remote work solutions, these innovative companies are solving critical business challenges with sophisticated software solutions. While established players continue to dominate the enterprise software market, a new generation of ambitious startups is emerging with fresh approaches to persistent business problems. Here are some of the most promising B2B SaaS companies that are worth keeping an eye on in 2025.
Best B2B SaaS Startups to Follow
Every year, new startups pull to the forefront of their industry through exciting innovation, tech, and industry-disrupting business models. We’ve rounded up the best B2B SaaS startups of 2025 that startup-lovers, investors, and aspiring entrepreneurs should follow.
Disclaimer: With so many exciting startups launching and growing worldwide, we aren’t able to cover them all. Furthermore, the startups that are listed below aren’t officially ranked and are listed in no particular order.
1. CoSchedule
- Location: Bismarck, North Dakota
- Founder(s): Garrett Moon, Justin Walsh
- Founded In: 2013
- Funding: Debt Financing, $2.5 Million
- Investors Include: Gen7 Investments, Bullinger Enterprises, Sandin Holdings
CoSchedule is a martech company that provides cloud-based marketing management software designed specifically for marketing teams and organizations. The company’s flagship product is a marketing calendar and project management platform that helps teams plan, organize, and execute their marketing strategies in one centralized location. The platform includes features for content planning, social media scheduling, task management, and marketing analytics.
2. Remote
- Location: San Francisco, California
- Founder(s): Job van der Voort, Marcelo Lebre
- Founded In: 2019
- Funding: Series C, $506 Million
- Investors Include: 20VC, B Capital Group, Flat Capital
Remote provides global human resources (HR) solutions, specifically focusing on helping organizations hire and manage employees anywhere in the world. The company offers an all-in-one platform that handles international payroll, benefits, taxes, compliance, and other HR functions for distributed teams. Remote also acts as an employer of record (EOR) service, allowing companies to hire employees in countries where they don’t have legal entities.
3. Native AI
- Location: New York, New York
- Founder(s): Sarah Sanders, Frank Pica
- Founded In: 2018
- Funding: Later-Stage VC, $6.25 Million
- Investors Include: Plug and Play Tech Center, Jumpstart Ventures, Ivy Ventures
Native AI has developed an AI-powered platform focused on helping companies better understand and predict consumer behavior. This startup’s technology uses natural language processing (NLP) and machine learning (ML) to process vast amounts of consumer data, helping businesses make more informed decisions about product development, marketing strategies, and customer experience improvements. The company aims to differentiate itself by providing AI-driven insights that are both highly accurate and easily actionable while maintaining strong data privacy standards.
4. Ambition
- Location: Chattanooga, Tennessee
- Founder(s): Travis Truett, Jared Houghton, Brian Trautschold, Wes Kendall
- Founded In: 2013
- Funding: Series B, $23.5 Million
- Investors Include: Nashville Capital Network, Primus Capital, Chattanooga Renaissance Fund
Ambition provides a sales coaching and gamification platform designed to help sales teams improve their productivity and performance. The company’s software combines real-time analytics, coaching workflows, and recognition tools to help sales managers motivate their teams and drive better results. The platform integrates with common customer relationship management (CRM) systems and sales tools to automatically track key performance metrics and create customized competitions, leaderboards, and achievement systems.
5. Pinecone
- Location: San Francisco, California
- Founder(s): Edo Liberty
- Founded In: 2019
- Funding: Series B, $138 Million
- Investors Include: Andreessen Horowitz, Menlo Ventures, ICONIQ
Pinecone is a vector database company that provides infrastructure for ML applications — particularly those focused on vector similarity search. Founded in 2019 by Edo Liberty, a former research director for Amazon Web Services (AWS), the company offers a specialized database designed to handle vector embeddings. These vector embeddings are crucial for modern AI applications like semantic search, recommendation systems, and image recognition. Pinecone’s managed service allows developers and data scientists to efficiently store, update, and query large collections of high-dimensional vectors in real time.
6. Chili Piper
- Location: New York, New York
- Founder(s): Nicolas Vandenberghe, Alina Vandenberghe
- Founded In: 2016
- Funding: Series B, $54.2 Million
- Investors Include: Tiger Global Management, Lighter Capital, Alt Option Return
Chili Piper is a revenue acceleration platform that provides solutions that help B2B companies convert more inbound leads by automatically qualifying, routing, and scheduling meetings with sales representatives. The company’s flagship products include tools for instant lead routing, meeting scheduling, and calendar management, which integrate with major CRM platforms and marketing automation tools.
7. Mighty Networks
- Location: Palo Alto, California
- Founder(s): Gina Bianchini, Tim Herby, Thomas Aaron
- Founded In: 2010
- Funding: Series B, $71.8 Million
- Investors Include: LionTree Partners, Intel Capital, Ziff Capital Partners
Mighty Networks is a software platform that enables creators and entrepreneurs to build and monetize their own branded digital communities and courses. The company provides tools for creators to combine community, courses, memberships, and events in one centralized platform under their own brand. The platform differentiates itself from traditional social networks by focusing on meaningful community engagement and allowing creators to own their audience relationships and data.
8. Rippling
- Location: San Francisco, California
- Founder(s): Parker Conrad, Prasanna Sankar
- Founded In: 2016
- Funding: Series F, $1.4 Billion
- Investors Include: Bossa Invest, Dragoneer Investment Group, Camford Capital
Rippling offers a comprehensive platform that manages everything from payroll and benefits to device management and app access. This startup’s core innovation is its employee graph technology, which allows companies to automate numerous workforce processes through a single system. Specifically, when users hire or lose an employee, Rippling can automatically handle everything from payroll adjustments to computer access and app permissions.
9. DemoDesk
- Location: Munich, Germany
- Founder(s): Alex Popp, Veronika Riederle
- Founded In: 2017
- Funding: Series A, $11.3 Million
- Investors Include: Earl Grey Capital, Balderton Capital, Des Traynor
Demodesk is a sales enablement platform that specializes in providing virtual meeting and demo solutions specifically designed for sales teams. The company’s primary product is a browser-based sales meeting platform that helps sales representatives deliver more effective product demonstrations and remote sales presentations. The Demodesk platform differentiates itself from traditional screen-sharing tools by providing a virtual display that loads web applications in the cloud, ensuring consistent performance regardless of local internet conditions.